Shilajit: A Natural Dietary Supplement with Potential Health Benefits and Breakthrough discovery in Preventing Alzheimer's

Shilajit: A Natural Dietary Supplement with Potential Health Benefits and Breakthrough discovery in Preventing Alzheimer's

Introduction:Shilajit, also known as salajit, shilajatu, mimie, or mummiyo, is a natural substance found in the Himalayas and other regions, formed through the decomposition of certain plants by microorganisms. It has been used for centuries in Ayurvedic medicine as a rejuvenator and anti-aging compound. Shilajit is composed mainly of humic substances, particularly fulvic acid, which accounts for a significant portion of its nutraceutical compound. This article explores the origins, molecular composition, traditional uses, and potential benefits of shilajit, with a focus on its cognitive and neuroprotective properties.


Origins of Shilajit:Shilajit is believed to be produced through the decomposition of plant material by microorganisms over several centuries. While the main plants responsible for shilajit formation are Euphorbia royleana and Trifoliumrepens, other plant organisms and species have been found to generate shilajit as well. These include various molds and species like Asterella, Dumortiera, Marchantia, Pellia, Plagiochasma, and Stephenrencella-Anthoceros.


Molecular Composition of Shilajit: Shilajit is primarily composed of humic substances, including fulvic acid, which makes up 60% to 80% of the total compound. Fulvic acid is a low molecular weight compound that exhibits strong antioxidant properties and is known for its systemic effects as a complement activator. Shilajit also contains other organic molecules such as eldagic acid, fatty acids, resins, triterpenes, aromatic carboxylic acids, amino acids, and polyphenols. Its composition may vary depending on the region from which it is extracted.


Traditional Uses of Shilajit: In Ayurvedic medicine, shilajit is considered a rasayana, a compound that promotes physical strength and human health. It has been traditionally used for increasing longevity, rejuvenation, and as a treatment for various disorders, including genitourinary disorders, jaundice, digestive disorders, epilepsy, and nervous disorders. Shilajit has also been used to treat kidney stones, edema, hemorrhoids, and as an internal antiseptic.




Shilajit's Potential in Preventing Alzheimer's Disease:  A Breakthrough Discovery

Recent preclinical investigations have revealed potential uses of shilajit in various diseases and health conditions. These include its antiulcerogenic, antioxidant, cognitive and memory-enhancing, antidiabetic, anxiolytic, anti-inflammatory, analgesic, and neuroprotective properties. Fulvic acid, one of the active principles in shilajit, has shown promising results in preventing tau self-aggregation associated with Alzheimer's disease.


Fulvic acid is known for its antioxidant properties and has been shown to have potential benefits for cognitive disorders associated with aging. In the context of Alzheimer's disease, fulvic acid has been found to block the self-aggregation of tau protein, which is a key pathological feature of the disease. This suggests that fulvic acid could have a potential therapeutic role in Alzheimer's therapy.

Shilajit also contains other beneficial compounds such as eldagic acid, fatty acids, resins, triterpenes, polyphenols, and phenolic lipids. These components contribute to its antioxidant, anti-inflammatory, and memory-enhancing properties. Shilajit has been traditionally used in Ayurvedic medicine for various purposes, including rejuvenation, anti-aging, genitourinary disorders, digestive disorders, epilepsy, and nervous disorders.

While shilajit shows promise as a dietary supplement and potential therapy for cognitive disorders, including Alzheimer's disease, further research is needed to understand its mechanisms of action at the molecular and cellular levels. Additionally, clinical trials are necessary to evaluate its effectiveness and safety in humans.

It is worth noting that the paper acknowledges the potential risks associated with consuming unprocessed shilajit, such as the presence of mycotoxins, heavy metals, and other contaminants. Therefore, it is important to use purified and properly processed preparations of shilajit to ensure safety.

Potential Risks: While shilajit is generally considered safe, it is essential to use purified and ready-for-use preparations to avoid the risks of intoxication. Some shilajit products, especially those purchased online, may contain detectable levels of heavy metals and other contaminants. Proper purification methods and quality control measures are crucial to ensure the safety and therapeutic advantages of shilajit products.


To conclude, Shilajit is a natural dietary supplement with immense potential in promoting human health and preventing diseases. Its main active principle, fulvic acid, has shown promising effects in cognitive disorders and as a potential therapy for Alzheimer's disease. However, further investigations and well-developed clinical trials are necessary to fully understand the molecular and cellular mechanisms of action of shilajit's active principles. For more information on the research paper mentioned in this blog, please visit



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